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There are times where this will backfire, but I think the biggest advantage of this over Pyrostatic Pillar as a maindeck card is that you cant get locked under it by a bigger creature deck as easily because you can just chump block with it and go back to casting spells

Enervate, meet Arc Lightning as an instant

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Focusing almost primarily on the collecting part of the Pokemon TCG allows it to sidestep most of the pitfalls of mobile games

Outside of that, Louisoixs Sacrifice could see some experimentation alongside cards like Tamiyo, Inquisitive Student in Commander, but theres very little reason to play this card in constructed since Flare of Denial almost always exists as a superior alternative