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Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:10mg and cell membrane permeability

SKU: 69275039492

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Description

and cell membrane permeability

Product Name Thalidomide-O-PEG5-OH Synonyms Thalidomide-4'-O-PEG5-OH CAS Number 2484091-02-1 Related CAS Molecular Formula C23H30N2O10 Molecular Weight 494

Product Name Thalidomide-O-acetamido-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-C2-amine HCl CAS Number 2341841-02-7 Related CAS Molecular Formula C17H19ClN4O6 Molecular Weight 410

Product Name DOTA-C2-amine Synonyms CAS Number 150467-20-2 Related CAS Molecular Formula C18H34N6O7 Molecular Weight 446

Contains cereblon ligand Thalidomid and 5'-substituted heterocyclic linker

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:10mg and cell membrane permeabilitySOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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