DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-nitrogen 227 SMILES [H]C(=O)NC1=CC=CC=C1C(=O)C[C@H](N)C(O)=O Purity (HPLC)

227 SMILES [H]C(=O)NC1=CC=CC=C1C(=O)C[C@H](N)C(O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Azide-Dap(m-PEG4)-Val-Cit-OH Synonyms CAS Number Related CAS Molecular Formula C24H44N8O10 Molecular Weight 604

Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C45H59N11O14 Molecular Weight 978

Trametinib (GSK1120212

024 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-nitrogen 227 SMILES [H]C(=O)NC1=CC=CC=C1C(=O)C[C@H](N)C(O)=O Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to